Cognitive-motor interference in people with essential tremor

Sci Rep. 2024 Oct 8;14(1):23456. doi: 10.1038/s41598-024-74310-x.

Abstract

Adapting to different environments throughout daily activities requires flexibility in allocating attention. Compromised dual-tasking can hinder mobility, increase fall risk, and decrease functional independence in patients with essential tremor, who exhibit both mobility and cognitive impairments. We evaluated motor and cognitive dual-task effects and task prioritization in 15 people with Essential Tremor (ET) and 15 age-matched people without ET during a standard and more challenging water-carry TUG. Task-specific interference was evaluated by calculating motor and cognitive dual-task effects, whereas task prioritization was assessed by contrasting the cognitive dual-task effect with the motor dual-task effect. The simultaneous performance of two tasks did not differentially impact motor or cognitive performance in either group, and both groups prioritized cognitive task performance in standard and water-carry TUG assessments. This study enhances our understanding of motor-cognitive interactions in individuals with essential tremor. These insights could lead to patient-centered approaches to therapy to improve functional performance in dynamic daily environments.

Keywords: Attention; Cognition; Gait; Neurological; Physical function; Tremor.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Attention / physiology
  • Cognition* / physiology
  • Cognitive Dysfunction / physiopathology
  • Cognitive Dysfunction / psychology
  • Essential Tremor* / physiopathology
  • Essential Tremor* / psychology
  • Female
  • Humans
  • Male
  • Middle Aged
  • Psychomotor Performance / physiology
  • Task Performance and Analysis