Impact of Indoor Air Pollutants on the Cardiovascular Health Outcomes of Older Adults: Systematic Review

Clin Interv Aging. 2024 Oct 1:19:1629-1639. doi: 10.2147/CIA.S480054. eCollection 2024.

Abstract

Indoor air pollution accounts for approximately 3.8 million inopportune deaths annually at global level. Due to spending more time indoors, children and older adults are especially susceptible to the health risks of indoor air pollution. This review seeks to summarise existing knowledge on the cardiovascular health effects of three common indoor air pollutants, namely carbon monoxide (CO), particulate matter (PM2.5 and PM10), and Nitrogen dioxide (NO2), focusing on older adults. We systematically reviewed the literature (PROSPERO CRD42024479220) on PubMed, Google Scholar, Scopus, Web of Science and Embase. The search yielded 20,914 records. Two independent reviewers screened the articles using titles, abstracts, and full-length articles written in English. Upon a detailed assessment of all the records, the review considered 38 full-length articles. Several studies reported mortality, myocardial infarction, stroke, increased hospitalisation and increased emergency room visits due to exposure to indoor air pollution. A few studies reported arrhythmias, hypertension and Ischaemic heart disease due to exposure to indoor air pollutants. The increased mortality, morbidity, hospitalization, and emergency rooms visits resulting from indoor air pollution associated CVDs makes indoor air pollution a health risk for older adults. There is, therefore, a need to synthesize information on studies relate d to how the selected indoor air pollutants affected the cardiovascular health of older adults.

Keywords: PM10; PM2.5; hospitalisation; mortality; myocardial infarction; nitrogen dioxide; older adults; particulate matter; stroke.

Publication types

  • Systematic Review
  • Review

MeSH terms

  • Aged
  • Air Pollutants / adverse effects
  • Air Pollution, Indoor* / adverse effects
  • Carbon Monoxide / adverse effects
  • Cardiovascular Diseases* / epidemiology
  • Cardiovascular Diseases* / etiology
  • Environmental Exposure / adverse effects
  • Hospitalization / statistics & numerical data
  • Humans
  • Nitrogen Dioxide* / adverse effects
  • Particulate Matter* / adverse effects

Substances

  • Particulate Matter
  • Nitrogen Dioxide
  • Carbon Monoxide
  • Air Pollutants