Guillain-Barré Syndrome Complicated by Severe Acute Respiratory Distress Syndrome: A Case Report

Yao Sun; Huiying Zhao; Youzhong An

doi:10.2147/IMCRJ.S462543

Guillain-Barré Syndrome Complicated by Severe Acute Respiratory Distress Syndrome: A Case Report

Int Med Case Rep J. 2024 Sep 27:17:809-817. doi: 10.2147/IMCRJ.S462543. eCollection 2024.

Authors

Yao Sun¹, Huiying Zhao¹, Youzhong An¹

Affiliation

¹ Department of Critical Care Medicine, Peking University People's Hospital, Beijing, People's Republic of China.

Abstract

Guillain-Barré syndrome (GBS) stands out as the most prevalent and severe acute immune-mediated paralytic neuropathy. Approximately 30% of patients experience respiratory failure necessitating admission to the intensive care unit (ICU) and invasive mechanical ventilation. The management of diseases concomitant with acute respiratory distress syndrome (ARDS) poses significant challenges. This case report illustrates the swift development of ARDS in a patient with GBS, explores the utility of the biomarker neurofilament light chain, and highlights the unexpected advantages of proactive ARDS intervention.

Keywords: Guillain-Barré syndrome; case; severe acute respiratory distress syndrome; ventilation.

Publication types

Case Reports

Grants and funding

The research received the grant from the National Natural Science Foundation of China (NSFC) (NO. 82202366) and Beijing Key Clinical Specialty Outstanding Project.