Superior long-term patency of no-touch vein graft compared to conventional vein grafts in over 1500 consecutive patients

J Cardiothorac Surg. 2024 Oct 1;19(1):570. doi: 10.1186/s13019-024-03057-3.

Abstract

Objectives: To evaluate the long-term angiographic patency of saphenous vein grafts (SVG) harvested using the no-touch technique compared to the conventional technique.

Methods: This was a single-center, retrospective, cohort study. The inclusion criteria were individuals who underwent a CABG (coronary artery bypass grafting) between January 1995 and July 2020, and who successively needed a clinically-driven angiography. The primary endpoint was long-term patency. The secondary endpoints were differences in patency based on sub-group analysis (single vs. sequential graft, divided by target vessel).

Results: The study included 1520 individuals (618 no-touch, 825 conventional and 77 arterial grafts). The mean clinical follow-up time was 8.4 years ± 5.5 years. The patency per patient was 70.7% in the no-touch grafts vs. 46.7% in the conventional grafts (p < 0.001, OR = 2.8). The graft patency was 75.9% in the no-touch grafts vs. 62.8% in the conventional grafts (p < 0.001, OR = 1.8).

Conclusions: The no-touch vein grafts were associated with statistically significantly higher patency at long-term compared to the conventional grafts.

Clinical trial registration: NCT04656366, 7 December 2020.

Keywords: coronary artery bypass graft; major adverse cardiac events; no-touch; patency; saphenous vein; stent.

Publication types

  • Comparative Study

MeSH terms

  • Aged
  • Coronary Angiography / methods
  • Coronary Artery Bypass* / methods
  • Female
  • Follow-Up Studies
  • Graft Occlusion, Vascular
  • Humans
  • Male
  • Middle Aged
  • Retrospective Studies
  • Saphenous Vein* / transplantation
  • Time Factors
  • Tissue and Organ Harvesting / methods
  • Vascular Patency*

Associated data

  • ClinicalTrials.gov/NCT04656366