From pain level to pain experience: redefining acute pain assessment to enhance understanding of chronic postsurgical pain

Br J Anaesth. 2024 Nov;133(5):1021-1027. doi: 10.1016/j.bja.2024.08.003. Epub 2024 Sep 26.

Abstract

Background: Chronic postsurgical pain (CPSP) significantly impairs quality of life and poses a substantial healthcare burden, affecting up to a quarter of patients undergoing surgery. Although acute pain is recognised as a predictor for CPSP development, the role of patient experience remains underexplored. This study examines the predictive value of patient experience alongside traditional risk factors for CPSP after orthopaedic surgery.

Methods: An exploratory analysis was conducted on 294 patients from a multicentre randomised clinical trial comparing continuous perineural analgesia and single-injection nerve block in ambulatory orthopaedic surgeries. Patient experience was assessed using the Evaluation du Vecu de l'Anesthésie Générale (EVAN-G) validated questionnaire. Factors associated with CPSP at 90 days after surgery were identified through univariate and multivariate analyses, incorporating patient-reported outcomes and classical variables.

Results: Out of 219 patients with complete data, 63 (29%) developed CPSP at day 90. Multivariate analysis revealed a poor pain experience, as assessed by the pain dimension of EVAN-G on postoperative day 2, as an independent predictor of CPSP (odds ratio 6.45, 95% confidence interval 1.65-25.26, P<0.01). Poor pain experience was associated with an augmented risk of CPSP.

Conclusions: This study underscores the role of patient-reported outcomes, specifically the pain experience dimension captured by the EVAN-G scale, in prediction of CPSP 90 days after surgery. It suggests a shift from conventional assessments of pain intensity to a comprehensive understanding of pain experience, advocating for tailored pain management approaches that could reduce chronic pain, thereby improving patient quality of life and functional recovery.

Keywords: acute pain; ambulatory surgery; catastrophising; chronic postsurgical pain; orthopaedic surgery; patient experience; regional anaesthesia; rehabilitation; secondary analysis.

Publication types

  • Multicenter Study
  • Randomized Controlled Trial

MeSH terms

  • Acute Pain / diagnosis
  • Adult
  • Aged
  • Chronic Pain*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Nerve Block / methods
  • Orthopedic Procedures / adverse effects
  • Pain Measurement* / methods
  • Pain, Postoperative* / diagnosis
  • Quality of Life
  • Risk Factors