The impact of gas transfer on responses to exercise training in patients with pulmonary hypertension

Pulm Circ. 2024 Sep 25;14(3):e12438. doi: 10.1002/pul2.12438. eCollection 2024 Jul.

Abstract

Exercise training is recommended for pulmonary hypertension (PH). Post hoc analysis of the PH and Home-Based (PHAHB) trial stratified patients into two groups based on median diffusing capacity of the lungs for carbon monoxide (DLCO). Patients with higher DLCO had a greater improvement in physical activity performance in response to exercise training, compared to those with lower DLCO. DLCO may be an important consideration in prescribing exercise in PH.

Keywords: DLCO; exercise training program; outcome; pulmonary hypertension.