Antimicrobial resistance (AMR) poses a significant global health threat. Due to its complexity, holistic approaches focusing on the interconnected factors influencing AMR across One Health domains are necessary. This study adopts system dynamics with extensive stakeholder engagement to unravel feedback processes between factors driving AMR. Initial results indicate numerous feedback loops between AMR drivers, which are not restricted to healthcare settings alone. A simulation model will be built to test various One Health scenarios to support decision-making on mitigating AMR.
Keywords: One Health; antibiotic resistance; causal loop diagram.