Acute Liver Failure Induced by Provitalize: A Menopause Supplement Concocted From Herbs & Probiotics

ACG Case Rep J. 2024 Sep 20;11(9):e01509. doi: 10.14309/crj.0000000000001509. eCollection 2024 Sep.

Abstract

Drug-induced liver injury is one of the most common causes of acute liver failure in the Western world. Despite discontinuation of the offending agent, it can still tax a grim prognosis. We describe a case of a menopausal woman taking a herbal supplement called "Provitalize" to relieve hot flashes and bloating. This is the first case report of liver injury from this supplement. She initially presented with mild jaundice and elevated transaminases. Unfortunately, she rapidly progressed to encephalopathy, experienced multiorgan failure, and then died.

Keywords: ALF; DILI; acute liver failure; drug induced liver injury; herbal and dietary supplements; menopause supplement; moringa; piperine; provitalize; turmeric.

Publication types

  • Case Reports