Methocinnamox is a Potent and Long-Acting Antagonist that can Prevent and Reverse Opioid-Induced Respiratory Depression

J Pharmacol Exp Ther. 2024 Sep 18;391(1):1-3. doi: 10.1124/jpet.124.002205.

Authors

James A Carr¹, Daniel J Morgan²

Affiliations

¹ Department of Biology, Texas Tech University, Lubbock, Texas (J.A.C.) and Department of Biomedical Sciences, Marshall University, Huntington, West Virginia (D.J.M.).
² Department of Biology, Texas Tech University, Lubbock, Texas (J.A.C.) and Department of Biomedical Sciences, Marshall University, Huntington, West Virginia (D.J.M.) morganda@marshall.edu.

PMID: 39293858
DOI: 10.1124/jpet.124.002205

No abstract available

MeSH terms

Analgesics, Opioid* / adverse effects
Animals
Humans
Male
Narcotic Antagonists / pharmacology
Narcotic Antagonists / therapeutic use
Rats
Rats, Sprague-Dawley
Respiratory Insufficiency* / chemically induced
Respiratory Insufficiency* / prevention & control

Substances

Analgesics, Opioid
Narcotic Antagonists