Operative treatment of clavicle fractures results in more opioids prescribed as compared to non-operative management

Eur J Orthop Surg Traumatol. 2024 Dec;34(8):3881-3887. doi: 10.1007/s00590-024-04058-7. Epub 2024 Sep 13.

Abstract

Purpose: The operative treatment of mid-shaft clavicle fractures shows benefit in union rates, return to work, and lower pain scores relative to non-operative treatment. We sought to determine if the surgical treatment of isolated mid-shaft clavicle fractures would result in fewer opioids prescribed as compared to those managed non-operatively.

Methods: All mid-shaft clavicle fractures treated at a Level 1 trauma center were identified from 2012 to 2016. Demographics, fracture characteristics, surgical complications/outcomes, non-operative outcomes, and all narcotics prescribed for 6 months post-injury were collected. Narcotic prescriptions, in morphine equivalents (ME), were obtained through the state prescription drug monitoring program (PDMP).

Results: One hundred and ten operative and 48 non-operative patients were included. Age, gender, previous alcohol, tobacco or drug use, and final range of motion were similar between groups. Pre-treatment fracture shortening (1.8 cm vs. 0.7 cm, p < 0.001) and displacement (150% vs. 70%, p < 0.001) were greater in the operative group. Total ME's (604 vs. 187, p < 0.001) and post-operative ME's (420 vs. 187, p < 0.001) were greater for the operative group. In either group, no other variable influenced ME's prescribed.

Conclusion: Clavicles treated operatively receive substantially more opiates than those treated non-operatively, despite data suggesting that operative treatment makes clavicle fractures less painful. The total amount of narcotic analgesics obtained by operatively treated patients was over three times that obtained by non-operatively managed patients, which equates to 55 5 mg oxycodone pills or 85 5 mg hydrocodone pills per patient. While there may certainly be advantages to the operative treatment of clavicle fractures, they must be weighed against the risks of a significant increase in opiate prescribing and potential consumption.

Keywords: Clavicle fracture; Opioid; Prescription pain medication; Regional anesthesia; Surgical block.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Analgesics, Opioid* / therapeutic use
  • Clavicle* / injuries
  • Clavicle* / surgery
  • Female
  • Fracture Fixation / adverse effects
  • Fracture Fixation / methods
  • Fractures, Bone* / surgery
  • Humans
  • Male
  • Middle Aged
  • Pain, Postoperative* / drug therapy
  • Pain, Postoperative* / etiology
  • Retrospective Studies

Substances

  • Analgesics, Opioid