Reducing off-target effects of DdCBEs by reversing amino acid charge near DNA interaction sites

Cell Res. 2024 Dec;34(12):877-881. doi: 10.1038/s41422-024-01028-w. Epub 2024 Sep 10.

¹ Shenzhen Branch, Guangdong Laboratory for Lingnan Modern Agriculture, Key Laboratory of Synthetic Biology, Ministry of Agriculture and Rural Affairs, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen, Guangdong, China.
² Shenzhen Branch, Guangdong Laboratory for Lingnan Modern Agriculture, Key Laboratory of Synthetic Biology, Ministry of Agriculture and Rural Affairs, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen, Guangdong, China. zuoerwei@caas.cn.

^# Contributed equally.

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