Update on the Treatment of Salivary Gland Carcinomas

Danielle M Gillard; Zainab Farzal; William R Ryan

doi:10.1016/j.soc.2024.04.008

Update on the Treatment of Salivary Gland Carcinomas

Surg Oncol Clin N Am. 2024 Oct;33(4):747-760. doi: 10.1016/j.soc.2024.04.008. Epub 2024 Jul 16.

Authors

Danielle M Gillard¹, Zainab Farzal², William R Ryan³

Affiliations

¹ Department of Otolaryngology-Head and Neck Surgery, University of California San Francisco, San Francisco, CA, USA.
² Department of Otolaryngology-Head and Neck Surgery, University of California San Francisco, San Francisco, CA, USA; Department of Otolaryngology Head and Neck Surgery, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-9035, USA.
³ Department of Otolaryngology-Head and Neck Surgery, University of California San Francisco, San Francisco, CA, USA. Electronic address: William.ryan@ucsf.edu.

PMID: 39244292
DOI: 10.1016/j.soc.2024.04.008

Abstract

Salivary gland carcinoma is a rare form of head and neck carcinoma, but it comprises a variety of subsites and histologic subtypes that each present with unique clinical courses and management challenges. Preoperative work-up generally consists of fine-needle aspiration cytology and MRI. However, because of the large variety of subtypes, there are often challenges obtaining a histologic diagnosis before surgery. Upfront surgery at the primary site leads to the greatest improvement in survival. Posttreatment surveillance of these patients is important. This article discusses some of the current controversies in the management of salivary gland carcinomas.

Keywords: Acinic cell carcinoma; Adenoid cystic carcinoma; Mucoepidermoid carcinoma; Salivary gland carcinoma; Salivary gland malignancy.

Publication types

Review

MeSH terms

Humans
Salivary Gland Neoplasms* / diagnosis
Salivary Gland Neoplasms* / pathology
Salivary Gland Neoplasms* / therapy