Stress and Hypothalamic-Pituitary-Adrenal Axis: Effect on Prognosis of Dental Treatment

Dent Clin North Am. 2024 Oct;68(4):619-626. doi: 10.1016/j.cden.2024.07.003. Epub 2024 Aug 7.

Abstract

Stress is a process that activates neuronal, metabolic, and neuroendocrine mechanisms. The individual's response may be determined by variables such as genetic factors, environmental conditions, sex, and age, among others. These responses are critical for survival, and the involvement of the hypothalamic-pituitary-adrenal axis is necessary for adaptation, which through counter-regulatory mechanisms seeks to restore homeostasis. Dentists are aware that there are variations in people's response to treatment, and there are many patients in whom dental treatment generates an important source of stress, which in many cases leads to treatment avoidance behavior.

Keywords: HPA and dental prognosis; HPA and dentistry; Stress and dental prognosis; Stress and dentistry.

Publication types

  • Review

MeSH terms

  • Dental Care
  • Humans
  • Hypothalamo-Hypophyseal System* / physiopathology
  • Pituitary-Adrenal System* / physiopathology
  • Prognosis
  • Stress, Psychological* / physiopathology