A biopsychosocial questionnaire for patients with primer Sjögren's syndrome: The BETY-Biopsychosocial Questionnaire

Gamze Ahiskali; Orkun Tüfekçi; Nur Banu Karaca; Mustafa Ekici; Nazli Elif Nacar; Sinan Buran; Mine Kantar; Bilgen Apras Şule; Sedat Kiraz; Edibe Unal

doi:10.1093/mr/roae085

A biopsychosocial questionnaire for patients with primer Sjögren's syndrome: The BETY-Biopsychosocial Questionnaire

Mod Rheumatol. 2024 Sep 3:roae085. doi: 10.1093/mr/roae085. Online ahead of print.

Authors

Affiliations

¹ Hacettepe University, Graduate School of Health Sciences, Department of Physiotherapy and Rehabilitation, Ankara, Turkey.
² Hacettepe University, Faculty of Physical Therapy and Rehabilitation, Department of Physiotherapy and Rehabilitation, Ankara, Turkey.
³ Hacettepe University, Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, Ankara, Turkey.
⁴ Kahramanmaras Sutcu Imam University, Vocational School of Health Services, Department of Physiotherapy, Kahramanmaras, Turkey.
⁵ Sakarya University, Faculty of Medicine, Department of Physical Medicine and Rehabilitation, Division of Rheumatology, Sakarya, Turkey.

PMID: 39223691
DOI: 10.1093/mr/roae085

Abstract

Objective: The BETY-Biopsychosocial Questionnaire (BETY-BQ) is a scale developed to assess the biopsychosocial domains of patients with rheumatic diseases under a single roof. The study aimed to determine the validity and reliability of the BETY-BQ in patients with primary Sjögren's Syndrome (pSS).

Methods: At enrollment and one week, 91 patients with pSS completed the BETY-BQ. Construct validity was measured by correlating the BETY-BQ total score responses with the Health Assessment Questionnaire (HAQ), Hospital Anxiety and Depression Scale (HADS), 36-Item Short-Form Health Survey (SF-36), EULAR Sjögren's Syndrome Patient Reported Index (ESSPRI), EULAR Sjögren's Syndrome Disease Activity Index (ESSDAI), Primary Sjögren's Syndrome Quality of Life questionnaire (PSS-QoL), and Euro-QoL 5D (EQ-5D).

Results: The BETY-BQ correlated high to moderate with HAQ, bodily pain subscale of SF-36, Euro Qol-5D, PSS-QoL, HADS, and ESSPRI (0.776 to 0.557, p <0.05). Spearman's correlation coefficients between BETY-BQ total scores at baseline and average one week were very high (rho = 0.98, <0.001) and indicated substantial agreement between test-retest scores (ICC = 0.99, <0.001). Internal consistency reliability at baseline was 0.91 for the BETY-BQ.

Conclusions: BETY-BQ is valid and reliable for assessing biopsychosocial status in patients with pSS and can be used to measure outcomes in pSS.

Keywords: Sjogren; patient-report outcomes; psychosocial; quality of life; rheumatic diseases.

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