Objective: To investigate the use of folded flap for repair of laryngeal and hypopharyngeal defect and the clinical efficacies of laryngeal and hypopharyngeal function reconstructions after surgery of piriform sinus cancer. Methods: A retrospective analysis was performed for 10 cases of piriform sinus cancer that were treated in the Second Norman Bethune Hospital of Jilin University from January 2020 to April 2023 and all patients were males, aged 42-68 years. The first choice of treatment for all patients was surgery. After function neck dissection and tracheotomy, partial laryngectomy and hypopharyngectomy were carried out. The folded island flaps were prepared and used for the repairs of laryngeal and hypopharyngeal defects and the reconstructions laryngeal and hypopharyngeal functions. The patients were followed up. Results: The laryngeal and pharyngeal cavities were reconstructed well in 10 patients, and all the flaps survived, with no case of pharyngeal fistula. All patients were able to eat normally through the mouth at 2 weeks after surgery without obvious choking, and 4 patients completed the swallowing function evaluation without aspiration or only a small amount of aspiration. All the 10 patients underwent postoperative radiotherapy. The postoperative follow-up time was 5.4-41.4 months, and there was no case with tumor recurrence or death. Laryngoscopy showed that 8 patients had a spacious new laryngeal orifice, which met the conditions for extubation, of whom 7 patients had their tracheal tubes removed and 1 patient was still under observation, and that 2 patients had a slightly narrowed new laryngeal orifice due to a thick skin flap, with further follow-up observation. All patients retained their phonatory functions after surgery. Conclusion: Folded island flap can be used for the function reconstructions of the larynx and hypopharynx after surgery of pyriform sinus cancer.
目的： 应用折叠皮瓣修复梨状窝癌手术部分喉及部分下咽缺损，并观察其喉功能重建及下咽梨状窝成形后的临床疗效。 方法： 回顾性分析2020年1月至2023年4月吉林大学白求恩第二医院收治，采用折叠岛状皮瓣修复的10例梨状窝癌病例，均为男性，年龄42~68岁。本组首选治疗方案均为手术治疗，颈淋巴清扫及气管切开后，行喉部分切除+下咽病变切除，取制备好的皮瓣进行折叠修复（9例选取颏下瓣，1例选取锁骨上皮瓣），重建恢复喉及下咽的生理性解剖结构，其中重点重建的结构是披裂、杓状会厌襞及梨状窝。随访并总结临床疗效。 结果： 10例患者术后喉与咽腔结构重建良好，皮瓣全部成活，无咽瘘发生。术后2周患者均正常经口进食，无明显呛咳；其中4例患者完成吞咽功能评估，无误吸或仅产生少量误吸。患者术后均行放疗。术后随访时间为5.4~41.4个月，无肿瘤复发或死亡。喉镜示8例患者新喉口宽敞，满足拔管条件，其中7例患者已拔除气管套管，1例堵管观察中；2例患者因皮瓣较厚，新喉口略狭窄。患者术后均保留发音功能。 结论： 折叠岛状皮瓣可恢复喉及下咽的生理性解剖结构，可用于喉功能重建及梨状窝成形。.