Self-assembled Fe3O4-COOH @ hydrogen-bonded organic framework composites for magnetic solid-phase extraction of tetracycline in food samples coupled with HPLC determination

Talanta. 2024 Dec 1:280:126746. doi: 10.1016/j.talanta.2024.126746. Epub 2024 Aug 23.

Abstract

Magnetic solid-phase extraction (MSPE) technology for tetracycline (TCC) was developed by employing the novel and pre-designed Fe3O4-COOH@hydrogen-bonded organic frameworks (HOFs) adsorbents in complex food samples. The HOF shell was grown onto the Fe3O4-COOH core by in-situ self-assembled method. The excellent MSPE performances with less solvent, less adsorbent and time consumption were derived from the hydrogen bonding, π-π and hydrophobic interactions between HOF shell and TCC. Combined with HPLC analysis, Fe3O4@ HOFs adsorbent reduced matrix effects and the established MSPE-HPLC method for TCC gave the linearity of 0.001-6 μg mL-1 with the limit of detection 0.0003 μg mL-1. The recoveries in pure milk, canned yellow peach and carrot were 82.4-103.7 %. The method provided a simple, efficient and dependable alternative to monitor trace TCC antibiotics in food or environmental samples.

Keywords: HPLC; Hydrogen-bonded organic frameworks; Magnetic solid phase extraction; Tetracycline.

MeSH terms

  • Adsorption
  • Animals
  • Anti-Bacterial Agents / analysis
  • Anti-Bacterial Agents / chemistry
  • Anti-Bacterial Agents / isolation & purification
  • Chromatography, High Pressure Liquid / methods
  • Daucus carota / chemistry
  • Ferrosoferric Oxide / chemistry
  • Food Analysis / methods
  • Food Contamination* / analysis
  • Hydrogen Bonding
  • Limit of Detection
  • Magnetic Phenomena
  • Metal-Organic Frameworks* / chemistry
  • Milk / chemistry
  • Solid Phase Extraction* / methods
  • Tetracycline* / analysis
  • Tetracycline* / chemistry
  • Tetracycline* / isolation & purification

Substances

  • Tetracycline
  • Metal-Organic Frameworks
  • Anti-Bacterial Agents
  • Ferrosoferric Oxide