An oncolytic adenovirus co-expressing a bi-specific T cell engager and IL-2 for the treatment of ovarian cancer

MeSH terms

• Adenoviridae* / genetics
• Animals
• Cell Line, Tumor
• Female
• Genetic Therapy / methods
• Genetic Vectors / administration & dosage
• Genetic Vectors / genetics
• Humans
• Interleukin-2* / genetics
• Interleukin-2* / metabolism
• Mice
• Oncolytic Virotherapy* / methods
• Oncolytic Viruses* / genetics
• Oncolytic Viruses* / immunology
• Ovarian Neoplasms* / genetics
• Ovarian Neoplasms* / immunology
• Ovarian Neoplasms* / therapy
• T-Lymphocytes / immunology
• T-Lymphocytes / metabolism
• Xenograft Model Antitumor Assays