Hypertension Prevalence, Treatment, and Control 90 Days After Acute Stroke Among Mexican American and Non-Hispanic White Adults

J Am Heart Assoc. 2024 Aug 20;13(16):e034252. doi: 10.1161/JAHA.124.034252. Epub 2024 Aug 19.

Abstract

Background: High blood pressure (BP) increases recurrent stroke risk.

Methods and results: We assessed hypertension prevalence, treatment, control, medication adherence, and predictors of uncontrolled BP 90 days after ischemic or hemorrhagic stroke among 561 Mexican American and non-Hispanic White (NHW) survivors of stroke from the BASIC (Brain Attack Surveillance in Corpus Christi) cohort from 2011 to 2014. Uncontrolled BP was defined as average BP ≥140/90 mm Hg at 90 days poststroke. Hypertension was uncontrolled BP or antihypertensive medication prescribed or hypertension history. Treatment was antihypertensive use. Adherence was missing zero antihypertensive doses per week. We investigated predictors of uncontrolled BP using logistic regression adjusting for patient factors. Median (interquartile range) age was 68 (59-78) years, 64% were Mexican American, and 90% of strokes were ischemic. Overall, 94.3% of survivors of stroke had hypertension (95.6% Mexican American versus 92.0% non-Hispanic White; P=0.09). Of these, 87.9% were treated (87.3% Mexican American versus 89.1% non-Hispanic White; P=0.54). Among the total population, 38.3% (95% CI, 34.4%-42.4%) had uncontrolled BP. Among those with uncontrolled BP prescribed an antihypertensive, 84.5% reported treatment adherence (95% CI, 78.8%-89.3%). Uncontrolled BP 90 days poststroke was less likely in patients with stroke who had a primary care physician (adjusted odds ratio [aOR], 0.45 [95% CI, 0.24-0.83]; P=0.01), greater stroke severity (aOR per-1-point-higher National Institutes of Health Stroke Scale score, 0.96 [95% CI, 0.93-0.99]; P=0.02), or more depressive symptoms (aOR per-1-point-higher Personal Health Questionnaire Depression Scale-8 score, 0.95 [95% CI, 0.92-0.99] among those with a history of hypertension at baseline; P=0.009).

Conclusions: Greater than one third of survivors of stroke have uncontrolled BP at 90 days poststroke in this population-based study. Interventions are needed to improve BP control after stroke.

Keywords: dementia; mild cognitive impairment; quality of health care; stroke.

MeSH terms

  • Aged
  • Antihypertensive Agents* / therapeutic use
  • Blood Pressure / drug effects
  • Female
  • Hemorrhagic Stroke / epidemiology
  • Hemorrhagic Stroke / ethnology
  • Humans
  • Hypertension* / drug therapy
  • Hypertension* / epidemiology
  • Hypertension* / ethnology
  • Hypertension* / physiopathology
  • Ischemic Stroke / diagnosis
  • Ischemic Stroke / epidemiology
  • Ischemic Stroke / ethnology
  • Ischemic Stroke / therapy
  • Male
  • Medication Adherence
  • Mexican Americans* / statistics & numerical data
  • Middle Aged
  • Prevalence
  • Risk Factors
  • Stroke / epidemiology
  • Stroke / ethnology
  • Texas / epidemiology
  • Time Factors
  • Treatment Outcome
  • White People* / statistics & numerical data

Substances

  • Antihypertensive Agents