Clinical Features and Risk Factors for Baker's Cyst in Patients with Rheumatoid Arthritis

Wan Lan Jiang; Ting Xu; Bi Qing Zhang; Lu Zhang; Min Wu; Wen Xie

doi:10.1093/mr/roae063

Clinical Features and Risk Factors for Baker's Cyst in Patients with Rheumatoid Arthritis

Mod Rheumatol. 2024 Aug 9:roae063. doi: 10.1093/mr/roae063. Online ahead of print.

Authors

Wan Lan Jiang¹, Ting Xu¹, Bi Qing Zhang², Lu Zhang¹, Min Wu¹, Wen Xie¹

Affiliations

¹ Department of Rheumatology and Immunology, The Third Affiliated Hospital of Soochow University, Changzhou, China.
² Department of Traditional Chinese Medicine, The Third Affiliated Hospital of Soochow University, Changzhou, China.

PMID: 39119677
DOI: 10.1093/mr/roae063

Abstract

Objectives: Baker's cyst (BC) is a complex complication of rheumatoid arthritis (RA), with a poor prognosis. This paper aimed to analyze the clinical features and risk factors for BC in patients with RA to assist clinicians in early warning and appropriate action.

Methods: The Clinical features of hospitalized RA patients with knee affected were analyzed retrospectively. The R software was used for the statistical analysis, while logistic regression analyses were used to determine independent risk factors.

Results: A total of 367 RA patients with knee affected were studied, and BC was diagnosis in 15.3% of them. The BC group exhibited a higher proportion of knee-only affected than the non-BC group (p < 0.05), while the attributes linked to disease activity exhibited no disparity. Logistic regression analyses selected two independent risk factors for BC: knee-only affected and anemia. 26.8% of patients with BC developed rupture, exhibiting a higher proportion of knee-only affected (p < 0.05), compared to those unruptured.

Conclusions: The occurrence and rupture of BC in RA patients were significantly related to local inflammation, but not to systemic one. Incorporating local treatment may be a more advantageous option compared to solely relying on systemic therapy.

Keywords: Baker’s cyst; Knee joint; Rheumatoid arthritis; Risk factors.

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