Knowledge of HPV vaccination and associated HNC and treatment decision-making among minority populations

Matthew E Lin; Oluwatobiloba Ayo-Ajibola; Ryan Davis; Tyler J Gallagher; Carlos X Castellanos; Jonathan D West; Margaret Nurimba; Niels C Kokot; Tamara Chambers

doi:10.1016/j.amjoto.2024.104458

Knowledge of HPV vaccination and associated HNC and treatment decision-making among minority populations

Am J Otolaryngol. 2024 Nov-Dec;45(6):104458. doi: 10.1016/j.amjoto.2024.104458. Epub 2024 Aug 3.

Authors

Matthew E Lin¹, Oluwatobiloba Ayo-Ajibola², Ryan Davis², Tyler J Gallagher², Carlos X Castellanos¹, Jonathan D West³, Margaret Nurimba³, Niels C Kokot³, Tamara Chambers⁴

Affiliations

¹ Department of Head and Neck Surgery, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, CA, USA.
² Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA.
³ Caruso Department of Otolaryngology-Head & Neck Surgery, Keck, School of Medicine of the University of Southern California, Los Angeles, CA, USA.
⁴ Caruso Department of Otolaryngology-Head & Neck Surgery, Keck, School of Medicine of the University of Southern California, Los Angeles, CA, USA. Electronic address: Tamara.Chambers@med.usc.edu.

PMID: 39116721
DOI: 10.1016/j.amjoto.2024.104458

Abstract

Objective: Understand vaccination knowledge and barriers to vaccination among minority adults.

Study design: Cross-sectional survey.

Setting: Otolaryngology clinics at a safety net hospital and a tertiary academic center and a head and neck cancer screening event.

Methods: Survey was administered to consenting patients. Descriptive statistics and significance testing were used to characterize the data, with non-minority respondents as controls. Multivariate logistic regression was used to understand factors associated with vaccination.

Results: HPV vaccination among our 241 respondents (n = 41, 17.67 %) and their qualifying children (n = 52, 33.55 %) was low. Non-vaccinated minorities were significantly more likely to express interest in HPV vaccination (28.66 % vs 8.66 %, p = 0.016). Minority patients were significantly less knowledgeable about HPV causing cervical (88.64 % vs 72.45 %, p = 0.024) and head and neck (68.18 % vs 44.90 %, p = 0.005) cancer and were also less aware of HPV infection (95.45 % vs 81.12 %, p = 0.020) among non-women. Lack of knowledge about the HPV vaccine was the most cited reason why minority patients did not or were uninterested in vaccination for themselves or their children. In a multivariable logistic regression of factors associated with HPV vaccination, only increased age demonstrated a significant association with vaccination likelihood (OR = 0.91, 95 % CI = [0.88-0.95], p < 0.001).

Conclusion: Reported HPV vaccination rates were low for both white and minority patients but did not significantly vary on univariate or multivariate analysis. However, minority respondents were significantly less knowledgeable about HPV and its manifestations; they most often cited inadequate knowledge as why did not receive or were uninterested in HPV vaccination. As such, HPV vaccination educational interventions may raise vaccination rates among minority populations.

Keywords: Gardasil; HPV; HPV vaccination; Patient knowledge; Treatment decision making.

MeSH terms

Adolescent
Adult
Cross-Sectional Studies
Decision Making
Female
Head and Neck Neoplasms* / virology
Health Knowledge, Attitudes, Practice*
Humans
Logistic Models
Male
Middle Aged
Minority Groups* / statistics & numerical data
Papillomavirus Infections* / prevention & control
Papillomavirus Vaccines* / administration & dosage
Surveys and Questionnaires
Vaccination* / statistics & numerical data
Young Adult

Substances

Papillomavirus Vaccines