FDG PET/CT in an Interesting Case of Paraneoplastic Relapsing Polychondritis Associated With Adenocarcinoma of the Lung

Clin Nucl Med. 2024 Sep 1;49(9):e482-e483. doi: 10.1097/RLU.0000000000005345. Epub 2024 Jul 31.

Abstract

Relapsing polychondritis (RP) is an uncommon autoimmune disease that causes inflammation of the cartilage and proteoglycan-rich structures, including the ear, nose, and airway. Paraneoplastic RP is a subset of RP that occurs in some individuals following the detection and treatment of certain types of cancers. FDG PET/CT helps with early diagnosis of RP, identifying inflammatory areas even in the absence of symptoms, and guiding the selection of appropriate biopsy sites. Here, we present a case of adenocarcinoma of the lung presenting with paraneoplastic symptoms of RP as initial presentation, and symptoms were resolved after 3 cycles of chemotherapy.

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma of Lung* / complications
  • Adenocarcinoma of Lung* / diagnostic imaging
  • Adenocarcinoma* / complications
  • Adenocarcinoma* / diagnostic imaging
  • Fluorodeoxyglucose F18*
  • Humans
  • Lung Neoplasms* / complications
  • Lung Neoplasms* / diagnostic imaging
  • Male
  • Middle Aged
  • Paraneoplastic Syndromes / diagnostic imaging
  • Polychondritis, Relapsing* / complications
  • Polychondritis, Relapsing* / diagnostic imaging
  • Positron Emission Tomography Computed Tomography*
  • Tomography, X-Ray Computed

Substances

  • Fluorodeoxyglucose F18