Linking APOE4/4 genotype to microglial lipid droplets and neurotoxicity in Alzheimer's disease
Transl Neurodegener
.
2024 Jul 30;13(1):38.
doi: 10.1186/s40035-024-00433-w.
Authors
Hao Huang
1
2
,
Rong Xiang
3
4
,
Riqiang Yan
5
Affiliations
1
Department of Cell Biology, School of Life Sciences, Central South University, Changsha, Hunan, China.
2
Hunan Key Laboratory of Organ Fibrosis, Central South University, Changsha, Hunan, China.
3
Department of Cell Biology, School of Life Sciences, Central South University, Changsha, Hunan, China. shirlesmile@csu.edu.cn.
4
Hunan Key Laboratory of Organ Fibrosis, Central South University, Changsha, Hunan, China. shirlesmile@csu.edu.cn.
5
Department of Neuroscience, University of Connecticut Health, Farmington, CT, USA. riyan@uchc.edu.
PMID:
39080732
PMCID:
PMC11290272
DOI:
10.1186/s40035-024-00433-w
No abstract available
Publication types
Editorial
MeSH terms
Alzheimer Disease* / genetics
Alzheimer Disease* / metabolism
Apolipoprotein E4* / genetics
Genotype
Humans
Lipid Droplets* / metabolism
Microglia* / metabolism
Substances
Apolipoprotein E4
Grants and funding
82300787/National Natural Science Foundation of China
82170598/National Natural Science Foundation of China
2022SK2034/Natural Science Foundation of Hunan Province
2022JJ30058/Natural Science Foundation of Hunan Province
2021Q11/Xiangya Hospital, Central South University