Contemporary Biomarker Strategies for Patients with Chest Pain

Stephen Boone; W Frank Peacock

doi:10.31083/j.rcm2305157

Contemporary Biomarker Strategies for Patients with Chest Pain

Rev Cardiovasc Med. 2022 Apr 27;23(5):157. doi: 10.31083/j.rcm2305157. eCollection 2022 May.

Authors

Stephen Boone¹, W Frank Peacock¹

Affiliation

¹ Department of Emergency Medicine, Baylor College of Medicine, 1 Baylor Plaza, Houston, TX 77030, USA.

Abstract

This review focuses on the strengths and limitations of conventional and high-sensitivity troponin in the evaluation of patients with suspected acute coronary syndromes. High-sensitivity troponin (hsTn) assays represent a significant innovation over prior generation troponin assays. Owing to superior analytical precision, hsTn permits more rapid "rule-in" and "rule-out" of myocardial infarction. Furthermore, hsTn assays, in properly implemented clinical pathways, permit a reduction in the portion of patients requiring extended observation and testing.

Keywords: acute coronary syndrome; biomarkers; chest pain; high sensitivity troponin; troponin.

Publication types

Review