About two unusual cases of pancreatic primary squamous cell carcinoma

Ismail Boujida; Kenza Horache; Sabrine Derqaoui; Ahmed Jahid; Fouad Zouaidia; Omar El-Aoufir; Zakia Bernoussi; Kaoutar Znati

doi:10.1093/jscr/rjae420

About two unusual cases of pancreatic primary squamous cell carcinoma

J Surg Case Rep. 2024 Jul 26;2024(7):rjae420. doi: 10.1093/jscr/rjae420. eCollection 2024 Jul.

Authors

Ismail Boujida^{1

2}, Kenza Horache^{2

3}, Sabrine Derqaoui^{1

2}, Ahmed Jahid^{1

2}, Fouad Zouaidia^{1

2}, Omar El-Aoufir^{2

3}, Zakia Bernoussi^{1

2}, Kaoutar Znati^{1

2}

Affiliations

¹ Department of Pathology, Ibn Sina University Hospital Center, 10100, Rabat, Morocco.
² Faculty of Medicine and Pharmacy, Mohammed 5 University, 10100, Rabat, Morocco.
³ Department of Radiology, Ibn Sina University Hospital Center, 10100, Rabat, Morocco.

Abstract

Pancreatic primary squamous cell carcinoma (PPSCC) is very uncommon. The major diagnostic method is histology, and it requires the exclusion of a metastasis from a different primary location (lung, esophagus…). Herein, we describe two cases of a PPSCC (one in the head and the other one in the tail and the body of the pancreas) with a brief review of literature. When it comes to the poorly differentiated PPSCC, immunohistochemistry (IHC) is crucial. Regretfully, there is currently no unanimity on treatment, and the outcome is dismal.

Keywords: immunohistochemistry; pancreatic neoplasm; squamous cell carcinoma.

Publication types

Case Reports