Unexpected Cataract Formation Following Valproate Treatment: A Case Report

Cureus. 2024 Jun 25;16(6):e63093. doi: 10.7759/cureus.63093. eCollection 2024 Jun.

Abstract

Valproic acid (VPA), or sodium valproate, is a frequently prescribed medication for many psychiatric conditions, notably for the management of bipolar affective disorder. While its common side effects are well known and thoroughly documented in medical literature, the occurrence of cataracts as a side effect is exceedingly rare. There is evidence of cataract formation with long-term use of VPA in a few studies. Recognizing this potential adverse effect is crucial. It is important to recommend that patients undergo regular eye examinations if they experience any visual disturbances or as a preventative measure to ensure effective management. This case report examines the unusual occurrence of cataract development associated with valproate use.

Keywords: bipolar affective disorder; cataract; valproate induced cataract; valproate toxicity; valproic acid.

Publication types

  • Case Reports