Rapidly Progressive Gait Disturbance and Extensive Iron Deposits in Late-Onset MPAN With a Pathogenic C19orf12 Variant: An 8-Year Follow-up

Neurology. 2024 Aug 27;103(4):e209724. doi: 10.1212/WNL.0000000000209724. Epub 2024 Jul 25.

Authors

Mayuko Imura¹, Keiichi Nakahara¹, Kentaro Hara¹, Hiroyo Yoshino¹, Kenya Nishioka¹, Nobutaka Hattori¹, Mitsuharu Ueda¹

Affiliation

¹ From the Department of Neurology (M.I., Keiichi Nakahara, K.H., M.U.), Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan; Research Institute for Diseases of Old Age (H.Y.); and Department of Neurology (Kenya Nishioka, N.H.), Graduate School of Medicine, Juntendo University, Tokyo, Japan.

PMID: 39052964
DOI: 10.1212/WNL.0000000000209724

No abstract available

Publication types

Case Reports

MeSH terms

Aged
Disease Progression
Female
Follow-Up Studies
Gait Disorders, Neurologic* / etiology
Gait Disorders, Neurologic* / genetics
Humans
Iron / metabolism
Male
Middle Aged
Mitochondrial Proteins / genetics

Substances

C19orf12 protein, human
Iron
Mitochondrial Proteins