Pediatric-Type Follicular Lymphoma of the Conjunctiva in Two Adolescents

J Pediatr Ophthalmol Strabismus. 2024 Jul-Aug;61(4):e33-e38. doi: 10.3928/01913913-20240517-01. Epub 2024 Jul 1.

Abstract

The authors present two cases of conjunctival pediatric-type follicular lymphoma. A 14-year-old Black boy and 14-year-old Black girl were each referred for evaluation of a painless salmon-colored conjunctival lesion. Both patients underwent excisional biopsy. Histopathology demonstrated follicles with germinal centers composed of atypical B-cells with high Ki67 proliferation index, positive staining for CD20, CD10, and BCL6, and negative for BCL2. This series contributes two cases to the limited literature and presents the first case reported in a female. [J Pediatr Ophthalmol Strabismus. 2024;61(4):e33-e38.].

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Biopsy
  • Conjunctiva* / pathology
  • Conjunctival Neoplasms* / diagnosis
  • Conjunctival Neoplasms* / pathology
  • Female
  • Humans
  • Lymphoma, Follicular* / diagnosis
  • Lymphoma, Follicular* / pathology
  • Male