In Israel, prevalence of sequence type 913, staphylococcal cassette chromosome mecIVa, spa type t991 methicillin-resistant Staphylococcus aureus lineage has surged among pediatric populations, predominantly in Arab and Orthodox Jewish communities. Antimicrobial resistance patterns vary by demographics. This lineage's spread and microevolution in the Middle East underscore the need for ongoing surveillance.
Keywords: Israel; MRSA; antimicrobial resistance; bacteria; local clone; methicillin-resistant Staphylococcus aureus; pediatric clone; whole-genome sequencing.