Correlation between hospital rates of survival to discharge and long-term survival for in-hospital cardiac arrest: Insights from Get With The Guidelines®-Resuscitation registry

Resuscitation. 2024 Sep:202:110322. doi: 10.1016/j.resuscitation.2024.110322. Epub 2024 Jul 18.

Abstract

Aim: Given challenges in collecting long-term outcomes for survivors of in-hospital cardiac arrest (IHCA), most studies have focused on in-hospital survival. We evaluated the correlation between a hospital's risk-standardized survival rate (RSSR) at hospital discharge for IHCA with its RSSR for long-term survival.

Methods: We identified patients ≥65 years of age with IHCA at 472 hospitals in Get With The Guidelines®-Resuscitation registry during 2000-2012, who could be linked to Medicare files to obtain post-discharge survival data. We constructed hierarchical logistic regression models to compute RSSR at discharge, and 30-day, 1-year, and 3-year RSSRs for each hospital. The association between in-hospital and long-term RSSR was evaluated with weighted Kappa coefficients.

Results: Among 56,231 Medicare beneficiaries (age 77.2 ± 7.5 years and 25,206 [44.8%] women), 10,536 (18.7%) survived to discharge and 8,485 (15.1%) survived to 30 days after discharge. Median in-hospital, 30-day, 1-year, and 3-year RSSRs were 18.6% (IQR, 16.7-20.4%), 14.9% (13.2-16.7%), 10.3% (9.1-12.1%), and 7.6% (6.8-8.8%), respectively. The weighted Kappa coefficient for the association between a hospital's RSSR at discharge with its 30-day, 1-year, and 3-year RSSRs were 0.72 (95% CI, 0.68-0.76), 0.56 (0.50-0.61), and 0.47 (0.41-0.53), respectively.

Conclusions: There was a strong correlation between a hospital's RSSR at discharge and its 30-day RSSR for IHCA, although this correlation weakens over time. Our findings suggest that a hospital's RSSR at discharge for IHCA may be a reasonable surrogate of its 30-day post-discharge survival and could be used by Medicare to benchmark hospital performance for this condition without collecting 30-day survival data.

Keywords: Advanced Cardiac Life Support; Cardiopulmonary Resuscitation; Heart Arrest; Outcome and Process Assessment, Health Care; Quality of Health Care; Survival Rate.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Cardiopulmonary Resuscitation* / methods
  • Cardiopulmonary Resuscitation* / statistics & numerical data
  • Female
  • Heart Arrest* / mortality
  • Heart Arrest* / therapy
  • Hospital Mortality
  • Humans
  • Male
  • Medicare / statistics & numerical data
  • Patient Discharge* / statistics & numerical data
  • Registries*
  • Survival Rate / trends
  • United States / epidemiology