Making Sense of Recovery From First Psychosis With Antipsychotic Medication: A Qualitative Phenomenological Study

Schizophr Bull. 2024 Nov 8;50(6):1508-1520. doi: 10.1093/schbul/sbae104.

Abstract

Background and hypothesis: Recovering from a first psychosis is a highly individual process and requires the person to make sense of their experiences. Clinicians, in turn, need to comprehend these first-person perspectives, creating a mutual sense-making dynamic. Antipsychotic medication is a substantial part of psychosis treatment. Providing insight in the lived experience of recovery with antipsychotics could improve the mutual understanding and help bridge the gap between the perspective of the clinician and that of the person recovering from psychosis.

Study design: 14 persons in recovery from a first psychosis with the use of antipsychotics were interviewed. Their narratives were analyzed using Interpretative Phenomenological Analysis (IPA).

Study results: Five overarching themes were found, representing important and meaningful experiences in recovering with antipsychotic medication. Theme 1: antipsychotics as external dampening (4 subthemes); Theme 2: shifting of realities; Theme 3: pace of recovery; Theme 4: antipsychotics' influence on identity; and Theme 5: is it truly the antipsychotics?

Conclusions: Our findings show that recovery from psychosis with antipsychotics is an all-encompassing, multi-faceted, and ambivalent experience. The themes found in this research could inspire clinicians to discuss less obvious aspects of the experience of recovering with antipsychotics. Even more so, paying attention to the first-person perspective could lead to a more thorough understanding and benefit therapeutic relationships.

Keywords: adherence; first-person perspective; identity; stigma; therapeutic relationship.

MeSH terms

  • Adult
  • Antipsychotic Agents* / administration & dosage
  • Antipsychotic Agents* / pharmacology
  • Female
  • Humans
  • Male
  • Middle Aged
  • Psychotic Disorders* / drug therapy
  • Psychotic Disorders* / rehabilitation
  • Qualitative Research*
  • Young Adult

Substances

  • Antipsychotic Agents