Central venous catheter-related right atrial thrombus in oncology patients: a case series of cardiovascular magnetic resonance studies

Eur Heart J Case Rep. 2024 Jun 28;8(7):ytae296. doi: 10.1093/ehjcr/ytae296. eCollection 2024 Jul.

Abstract

Background: Patients with cancer are at an increased risk of thrombus formation, often identified on routine echocardiogram in the right atrium. The 2022 ESC Guidelines on Cardio-oncology emphasize cardiac magnetic resonance (CMR) as the gold standard for thrombus identification.

Case summary: We present a case series of seven patients who underwent CMR due to right atrial mass suspected to result from central venous catheter-related right atrial thrombus. In all cases, CMR enabled accurate diagnosis of a thrombus. It also allowed to assess complete or partial resolution of the thrombi following anticoagulation on follow-up studies.

Discussion: The presence of a central venous catheter is recognized as a risk factor for thrombus formation, particularly when inappropriately advanced into the right atrium. The integration of CMR into the diagnostic pathway enabled precise thrombus identification and guidance for treatment in this population with a complex balance between cancer-related thrombotic and haemorrhagic risks.

Keywords: Cardiac magnetic resonance; Cardiac mass; Cardio-oncology; Case series; Thrombus.

Publication types

  • Case Reports