Atypical left-ventricular hypertrophy with apical aneurysm in leopard syndrome

Int J Cardiovasc Imaging. 2024 Aug;40(8):1809-1811. doi: 10.1007/s10554-024-03185-w. Epub 2024 Jul 8.

Abstract

Noonan Syndrome with Multiple Lentigines (NSML-formerly known as LEOPARD syndrome) is a rare autosomal dominant condition that usually exhibits cardiac involvement with hypertrophic cardiomyopathy (HCM). Here we present a case of a NSML patient with an unusual and patchy cardiac hypertrophy distribution.

Keywords: CMR; Noonan; TTE; atypical; hypertrophy.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Cardiomyopathy, Hypertrophic / complications
  • Cardiomyopathy, Hypertrophic / diagnostic imaging
  • Cardiomyopathy, Hypertrophic / physiopathology
  • Female
  • Heart Aneurysm* / complications
  • Heart Aneurysm* / diagnostic imaging
  • Humans
  • Hypertrophy, Left Ventricular* / diagnostic imaging
  • Hypertrophy, Left Ventricular* / physiopathology
  • LEOPARD Syndrome* / complications
  • LEOPARD Syndrome* / diagnostic imaging
  • LEOPARD Syndrome* / genetics
  • Male
  • Phenotype
  • Ventricular Function, Left