Advances in HIV Management During Pregnancy and Infant Feeding

Infect Dis Clin North Am. 2024 Sep;38(3):423-452. doi: 10.1016/j.idc.2024.06.005. Epub 2024 Jul 4.

Abstract

Recent advances in human immunodeficiency virus (HIV) management during pregnancy and infant feeding encompass several key elements: expanded HIV testing guidance; growing evidence of safety, efficacy, and pharmacokinetic data favoring the use of preferred antiretroviral therapy (ART) during pregnancy and breastfeeding; increasing advocacy for the inclusion of pregnant individuals with HIV in clinical trials to expedite access to new ART; and updated guidelines supporting shared decision-making for choice of infant feeding methods in people with HIV.

Keywords: Antiretroviral therapy; Breastfeeding; HIV; Infant feeding; Integrase inhibitors; Lactation; Pregnancy.

Publication types

  • Review

MeSH terms

  • Anti-HIV Agents / administration & dosage
  • Anti-HIV Agents / therapeutic use
  • Breast Feeding*
  • Female
  • HIV Infections* / drug therapy
  • Humans
  • Infant
  • Infant, Newborn
  • Infectious Disease Transmission, Vertical* / prevention & control
  • Pregnancy
  • Pregnancy Complications, Infectious* / drug therapy

Substances

  • Anti-HIV Agents