Treatment-free remission after third-line therapy with asciminib in chronic myeloid leukemia with an atypical e19a2 BCR::ABL1 transcript and T315I mutation

Leukemia. 2024 Sep;38(9):2037-2040. doi: 10.1038/s41375-024-02327-2. Epub 2024 Jul 4.
No abstract available

Publication types

  • Letter
  • Case Reports

MeSH terms

  • Female
  • Fusion Proteins, bcr-abl* / genetics
  • Humans
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive* / drug therapy
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive* / genetics
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive* / pathology
  • Male
  • Middle Aged
  • Mutation*
  • Niacinamide / analogs & derivatives
  • Protein Kinase Inhibitors / therapeutic use
  • Pyrazoles / therapeutic use
  • Remission Induction*

Substances

  • Fusion Proteins, bcr-abl
  • asciminib
  • Pyrazoles
  • Protein Kinase Inhibitors
  • Niacinamide