Newer Immunosuppressants for Rheumatologic Disease: Preoperative Considerations

Rheum Dis Clin North Am. 2024 Aug;50(3):545-557. doi: 10.1016/j.rdc.2024.03.006.

Abstract

With the advent of small-molecule immune modulators, recombinant fusion proteins, and monoclonal antibodies, treatment options for patients with rheumatic diseases are now broad. These agents carry significant risks and an individualized approach to each patient, balancing known risks and benefits, remains the most prudent course. This review summarizes the available immunosuppressant treatments, discusses their perioperative implications, and provides recommendations for their perioperative management.

Keywords: Biologic therapy; Medication therapy management; Perioperative period; Rheumatic diseases.

Publication types

  • Review

MeSH terms

  • Humans
  • Immunosuppressive Agents* / therapeutic use
  • Preoperative Care / methods
  • Rheumatic Diseases* / drug therapy

Substances

  • Immunosuppressive Agents