Abstract
We report a rare case of confirmed early neurosyphilis with serofast state in HIV-negative patient, with uncontrolled type 2 diabetes mellitus. Syphilitic meningitis was diagnosed initially on serology and cerebrospinal fluid (CSF) analysis. The patient had persistently raised non-treponemal titres on serum with negative CSF venereal disease research laboratory result, following treatment during 3 years of follow-up.
Keywords:
Neurosyphilis; cerebrospinal fluid; meningitis; nontreponemal antibodies; serofast.
MeSH terms
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Anti-Bacterial Agents / therapeutic use
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Antibodies, Bacterial / blood
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Antibodies, Bacterial / cerebrospinal fluid
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Diabetes Mellitus, Type 2 / complications
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Humans
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Male
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Middle Aged
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Neurosyphilis* / complications
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Neurosyphilis* / diagnosis
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Neurosyphilis* / drug therapy
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Treponema pallidum / immunology
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Treponema pallidum / isolation & purification
Substances
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Anti-Bacterial Agents
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Antibodies, Bacterial
Grants and funding
This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.