Pulse2AI: An Adaptive Framework to Standardize and Process Pulsatile Wearable Sensor Data for Clinical Applications

IEEE Open J Eng Med Biol. 2024 May 8:5:330-338. doi: 10.1109/OJEMB.2024.3398444. eCollection 2024.

Abstract

Goal: To establish Pulse2AI as a reproducible data preprocessing framework for pulsatile signals that generate high-quality machine-learning-ready datasets from raw wearable recordings. Methods: We proposed an end-to-end data preprocessing framework that adapts multiple pulsatile signal modalities and generates machine-learning-ready datasets agnostic to downstream medical tasks. Results: a dataset preprocessed by Pulse2AI improved systolic blood pressure estimation by 29.58%, from 11.41 to 8.03 mmHg in root-mean-square-error (RMSE) and its diastolic counterpart by 26.01%, from 7.93 to 5.87 mmHg in RMSE. For respiration rate (RR) estimation, Pulse2AI boosted performance by 19.69%, from 1.47 to 1.18 breaths per minute (BrPM) in mean-absolute-error (MAE). Conclusion: Pulse2AI turns pulsatile signals into machine learning (ML) ready datasets for arbitrary remote health monitoring tasks. We tested Pulse2AI on multiple pulsatile modalities and demonstrated its efficacy in two medical applications. This work bridges valuable assets in remote sensing and internet of medical things to ML-ready datasets for medical modeling.

Keywords: Bridge2AI; IoMT; ML for Healthcare; signal processing; wearable pulsatile signals.

Grants and funding

This work was supported by the National Institutes of Health under Grant 1R01HL151240-01A1 and Grant 1R21EB028486-01.