Care practices of contact lens solutions and microbial contamination among wearers in Ghana

Cont Lens Anterior Eye. 2024 Oct;47(5):102252. doi: 10.1016/j.clae.2024.102252. Epub 2024 Jun 17.

Abstract

Purpose: This study sought to assess contact lens solutions care practices, and their microbial contamination among contact lens wearers in Ghana and to profile their antibiotic susceptibility pattern.

Methods: The study employed a biphasic approach which involved a cross-sectional design that investigated participants' habits related to care for the solutions with a two-part questionnaire and a microbiological analysis of samples of contact lens care solutions of the participants for microbial contamination. A snowball sampling method provided access to 32 different contact lens wearers in four care facilities in Ghana. In most cases, the participants had no pre-existing familial relationship with each other or with the care facilities.

Results: Out of 32 samples of contact lens solutions, 30 were tested for microbial contamination. A total of 23 (76.67 %) samples of contact lens solution were found to be contaminated with Enterobacter sp. (34.80 %), Pseudomonas sp. (21.70 %), Bacilli sp. (21.70 %), Klebsiella sp. (17.20 %), and Escherichia coli (4.60 %). The duration of solution storage in the open bottle and nonadherence to manufacturer instructions for solution storage showed a statistically significant association with microbial contamination (p ≤ 0.05).

Conclusion: Contact lens care solutions have been found to harbour multiple antibiotic-resistant bacteria that are potentially pathogenic to the corneal surface. The contamination is associated with some unhealthy solution-care practices among wearers.

Keywords: Antimicrobial Susceptibility testing; Contact lens care solutions; Microbial contamination.

Publication types

  • Multicenter Study

MeSH terms

  • Adolescent
  • Adult
  • Anti-Bacterial Agents / pharmacology
  • Bacteria* / isolation & purification
  • Contact Lens Solutions* / pharmacology
  • Contact Lenses / microbiology
  • Cross-Sectional Studies
  • Drug Contamination
  • Equipment Contamination
  • Eye Infections, Bacterial / epidemiology
  • Eye Infections, Bacterial / microbiology
  • Eye Infections, Bacterial / prevention & control
  • Female
  • Ghana
  • Humans
  • Male
  • Microbial Sensitivity Tests
  • Middle Aged
  • Surveys and Questionnaires
  • Young Adult

Substances

  • Contact Lens Solutions
  • Anti-Bacterial Agents