Adherence to guideline recommendations for follow-up in patients with DCIS at a large teaching hospital in the Netherlands

Breast Cancer Res Treat. 2024 Oct;207(3):633-640. doi: 10.1007/s10549-024-07391-x. Epub 2024 Jun 14.

Abstract

Purpose: Ductal-carcinoma in situ (DCIS) is a pre-invasive form of breast cancer with good prognosis. Follow-up guidelines in the Netherlands are currently the same as for invasive breast cancer. Due to fear of invasive breast cancer or recurrence, it is hypothesized that follow-up for DCIS after treatment is more intense in practice resulting in potentially unnecessary high costs. This study investigates the follow-up in practice for patients with DCIS compared to the recommendations in order to inform clinicians and policy makers how to utilize these guidelines.

Methods: Patients diagnosed with pure DCIS between 2004 and 2014 were followed up until 2018. Information on duration and frequency of follow-up visits, reasons and decision makers for shortening, and prolonging follow-up was collected. Prolonged follow-up was defined as deviation from the Dutch guideline: more than 5 years of follow-up and older than 60 years.

Results: Of the 227 patients the mean number of visits per year was 1.4 and mean years of follow-up was 6.0. Thirty-three percent had prolonged follow-up and 26% shorter follow-up than recommended. A majority (78%) of decision for prolonged follow-up was being made by clinicians.

Conclusion: Follow-up duration is in almost half of patients with DCIS according to guidelines and with most prolonged follow-up only up to a year longer than recommended. In most cases suspicious findings and the timing of the population screening program appeared to cause prolonged follow-up. If accepted by patients and clinicians, future DCIS specific guidelines should address these reasons and tailor to the individual risks.

Keywords: Breast cancer; DCIS; Ductal-carcinoma in situ; Follow-up; Screening.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Breast Neoplasms* / epidemiology
  • Breast Neoplasms* / pathology
  • Breast Neoplasms* / therapy
  • Carcinoma, Intraductal, Noninfiltrating* / epidemiology
  • Carcinoma, Intraductal, Noninfiltrating* / pathology
  • Carcinoma, Intraductal, Noninfiltrating* / therapy
  • Female
  • Follow-Up Studies
  • Guideline Adherence* / statistics & numerical data
  • Hospitals, Teaching*
  • Humans
  • Middle Aged
  • Neoplasm Recurrence, Local / epidemiology
  • Netherlands / epidemiology
  • Practice Guidelines as Topic*