A Case of Deep Venous Thrombosis in an HIV-Infected Patient despite Therapeutic Anticoagulation

Wajeeha Aiman; Muhammad Ashar Ali; Navjot Grewal; Nyan Bethel; Andreas A Savopoulos; Gunwant Guron

doi:10.18502/ijhoscr.v18i2.15379

A Case of Deep Venous Thrombosis in an HIV-Infected Patient despite Therapeutic Anticoagulation

Int J Hematol Oncol Stem Cell Res. 2024 Apr 1;18(2):206-209. doi: 10.18502/ijhoscr.v18i2.15379.

Authors

Wajeeha Aiman¹, Muhammad Ashar Ali², Navjot Grewal¹, Nyan Bethel¹, Andreas A Savopoulos¹, Gunwant Guron¹

Affiliations

¹ Saint Michael's Medical Center, New York College of Medicine, Newark, NJ, USA.
² Saint Clare's and St. Mary's General Hospital, Denville, NJ, USA.

Abstract

Patients with human immunodeficiency virus (HIV) infection have an increased likelihood of venous thromboembolism (VTE) owing to factors such as acquired protein C and S deficiency, antiphospholipid antibody syndrome, and heightened levels of pro-inflammatory cytokines. This case report highlights an exceptionally uncommon occurrence of deep venous thrombosis in an HIV-infected patient receiving a therapeutic dose of enoxaparin. This underscores the need for cautious consideration of the risk of VTE in HIV-infected individuals, even with preventive or therapeutic anticoagulant treatment. Further research is recommended to investigate HIV as a potential risk factor of prophylactic anticoagulation.

Keywords: Anti-coagulants; Deep venous thrombosis; Enoxaparin; Human immunodeficiency virus (HIV).

Publication types

Case Reports