Electrochemotherapy in dogs and cats-A review

Vet Comp Oncol. 2024 Sep;22(3):311-321. doi: 10.1111/vco.12980. Epub 2024 Jun 12.

Abstract

Electrochemotherapy (ECT) is a treatment modality that combines the electroporation of cell membranes with chemotherapy to facilitate the transport of non-permeant molecules into cells. Several canine and feline studies have shown promising results, suggesting that ECT can be a valid adjuvant or alternative treatment option for some tumours. The objective of this paper is to provide a bibliographic review of the principles and applications of ECT in veterinary medicine and to compare to its use in human medicine.

Keywords: electrochemotherapy; electroporation; small animals; tumours.

Publication types

  • Review

MeSH terms

  • Animals
  • Antineoplastic Agents / therapeutic use
  • Cat Diseases* / drug therapy
  • Cats
  • Dog Diseases* / drug therapy
  • Dogs
  • Electrochemotherapy* / methods
  • Electrochemotherapy* / veterinary
  • Neoplasms* / drug therapy
  • Neoplasms* / veterinary

Substances

  • Antineoplastic Agents