A Retrospective Cohort Study of Disparities in Urine Drug Testing During the Perinatal Period in an Urban, Academic Medical Center

Matern Child Health J. 2024 Aug;28(8):1395-1403. doi: 10.1007/s10995-024-03940-4. Epub 2024 Jun 7.

Abstract

The purpose of this study was to evaluate disparities in urine drug testing (UDT) during perinatal care at a single academic medical center. This retrospective cohort study included patients who had a live birth and received prenatal care at our institution between 10/1/2015 and 9/30/2020. The primary outcomes were maternal UDT during pregnancy (UDTPN) and UDT only at delivery (UDTDEL). Secondary outcomes included the number of UDTs (UDTNUM) and the association between a positive UDT test result and race/ethnicity. Mixed model logistic regression and negative binomial regression with clustering based on prenatal care locations were used to control for confounders. Of 6,240 live births, 2,265 (36.3%) and 167 (2.7%) received UDTPN and UDTDEL, respectively. Black (OR 2.09, 95% CI 1.54-2.84) and individuals of Other races (OR 1.64, 95% CI 1.03-2.64) had greater odds of UDTPN compared to non-Hispanic White individuals. Black (beta = 1.12, p < 0.001) and Hispanic individuals (beta = 0.78, p < 0.001) also had a positive relationship with UDTNUM. Compared to individuals with non-Medicaid insurance, those insured by Medicaid had greater odds of UDTPN (OR 1.66, 95% CI 1.11-2.49) and had a positive relationship with UDTNUM (beta = 0.89, p < 0.001). No significant associations were found for UDTDEL and race/ethnicity. Despite receiving more UDT, Black individuals were not more likely to have a positive test result compared to non-Hispanic White individuals (OR 0.95, 95% CI 0.72-1.25). Our findings demonstrate persistent disparities in substance use testing during the perinatal period.

Keywords: Health disparities; Prenatal care; Substance use; Urine drug testing.

MeSH terms

  • Academic Medical Centers* / statistics & numerical data
  • Adult
  • Cohort Studies
  • Female
  • Healthcare Disparities* / statistics & numerical data
  • Humans
  • Perinatal Care / methods
  • Perinatal Care / statistics & numerical data
  • Pregnancy
  • Pregnancy Complications / diagnosis
  • Pregnancy Complications / urine
  • Prenatal Care / methods
  • Prenatal Care / statistics & numerical data
  • Retrospective Studies
  • Substance Abuse Detection* / methods
  • Substance Abuse Detection* / statistics & numerical data
  • Substance-Related Disorders / diagnosis
  • Substance-Related Disorders / epidemiology
  • Substance-Related Disorders / urine