Bibliometric insights into the inflammation and mitochondrial stress in ischemic stroke

Exp Neurol. 2024 Aug:378:114845. doi: 10.1016/j.expneurol.2024.114845. Epub 2024 Jun 3.

Abstract

Background: Research in the areas of inflammation and mitochondrial stress in ischemic stroke is rapidly expanding, but a comprehensive overview that integrates bibliometric trends with an in-depth review of molecular mechanisms is lacking.

Objective: To map the evolving landscape of research using bibliometric analysis and to detail the molecular mechanisms that underpin these trends, emphasizing their implications in ischemic stroke.

Methods: We conducted a bibliometric analysis to identify key trends, top contributors, and focal research themes. In addition, we review recent research advances in mitochondrial stress and inflammation in ischemic stroke to gain a detailed understanding of the pathophysiological processes involved.

Conclusion: Our integrative approach not only highlights the growing research interest and collaborations but also provides a detailed exploration of the molecular mechanisms that are central to the pathology of ischemic stroke. This synthesis offers valuable insights for researchers and paves the way for targeted therapeutic interventions.

Keywords: Bibliometrics; Inflammation; Ischemic stroke; Mitochondrial stress.

Publication types

  • Review

MeSH terms

  • Animals
  • Bibliometrics*
  • Humans
  • Inflammation* / metabolism
  • Inflammation* / pathology
  • Ischemic Stroke* / metabolism
  • Ischemic Stroke* / pathology
  • Mitochondria* / metabolism