Stubborn Swellings: A Rare Case of Kimura's Disease Presenting as Parotid Swellings

Cureus. 2024 May 3;16(5):e59570. doi: 10.7759/cureus.59570. eCollection 2024 May.

Abstract

Kimura disease (KD) is a rare chronic inflammatory disorder characterized by the development of painless subcutaneous nodules, predominantly in the head and neck region. Diagnosis relies on a high index of clinical suspicion and clinicopathological correlation, with core biopsy serving as the gold standard for a definitive diagnosis. While the disease itself is benign, it can cause significant morbidity if left untreated. This case report describes a 48-year-old male who presented with bilateral infraauricular swellings, pruritus, and elevated serum IgE levels along with eosinophilia. Imaging and histopathological correlation confirmed the diagnosis of KD. Combination therapy of corticosteroids and cyclosporine resulted in significant clinical improvement, highlighting the efficacy of the approach while avoiding surgical resection. This case emphasizes the importance of radiologic-pathologic correlation along with the use of serology to effectively diagnose KD, even in atypical presentations.

Keywords: angiolymphoid hyperplasia with eosinophilia; cervical lymphadenopathy; head and neck swellings; kimura's disease; peripheral eosinophilia; radio-pathological correlation.

Publication types

  • Case Reports