Toward Transparency and Trust: Assessing and Addressing Key Ethical Concerns in Normothermic Regional Perfusion

J Law Med Ethics. 2024;52(1):178-182. doi: 10.1017/jme.2024.52. Epub 2024 May 31.

Abstract

Normothermic Regional Perfusion, or NRP, is a method of donated organ reperfusion using cardiopulmonary bypass or a modified extracorporeal membrane oxygenation (ECMO) circuit after circulatory death while leaving organs in the dead donor's corpse. Despite its potential, several key ethical issues remain unaddressed by this technology.

Keywords: Circulatory Death; Medical Ethics; Normothermic Regional Perfusion (Nrp); Safeguards.

MeSH terms

  • Cardiopulmonary Bypass / ethics
  • Extracorporeal Membrane Oxygenation / ethics
  • Humans
  • Organ Preservation / ethics
  • Organ Preservation / methods
  • Perfusion
  • Tissue and Organ Procurement / ethics
  • Trust*