Platelet-rich plasma therapy for postoperative esophageal fistula in a pediatric patient

J Surg Case Rep. 2024 May 30;2024(5):rjae350. doi: 10.1093/jscr/rjae350. eCollection 2024 May.

Abstract

Postoperative management of esophagocutaneous fistulas in pediatric patients is challenging, often resulting in prolonged hospitalization and increased morbidity. Platelet-rich plasma (PRP) has emerged as a promising adjunctive treatment for such complications. We present the case of a 7-month-old infant who developed an esophago-cutaneous fistula following esophagocoloplasty for esophageal atresia type A. Despite initial conservative management, the fistula persisted, prompting the application of PRP gel derived from umbilical cord blood. After four applications of PRP, complete closure of the fistula was achieved, leading to both functional and aesthetic results. This case highlights the potential of PRP in managing refractory postoperative esophageal fistulas in pediatric patients and underscores the need for further research to optimize treatment protocols and validate its efficacy for this sort of complications.

Keywords: colorectal surgery; pediatric surgery; plastic surgery; upper GI surgery; urology.

Publication types

  • Case Reports