Smoking-Related Interstitial Lung Disease and Emphysema

Abstract

Diagnosis and treatment of patients with smoking-related lung diseases often requires multidisciplinary contributions to optimize care. Imaging plays a key role in characterizing the underlying disease, quantifying its severity, identifying potential complications, and directing management. The primary goal of this article is to provide an overview of the imaging findings and distinguishing features of smoking-related lung diseases, specifically, emphysema/chronic obstructive pulmonary disease, respiratory bronchiolitis-interstitial lung disease, smoking-related interstitial fibrosis, desquamative interstitial pneumonitis, combined pulmonary fibrosis and emphysema, pulmonary Langerhans cell histiocytosis, and E-cigarette or vaping related lung injury.

Keywords: Combined pulmonary fibrosis and emphysema; Computed tomography; Desquamative interstitial pneumonia; Emphysema; Interstitial lung disease; Langerhans cell histiocytosis; Smoking; Smoking-related interstitial fibrosis.