Retrospective evaluation of the utility of shock index to determine the presence of congestive heart failure in dogs with myxomatous mitral valve disease (2019-2021): 98 cases

J Vet Emerg Crit Care (San Antonio). 2024 May-Jun;34(3):231-237. doi: 10.1111/vec.13379. Epub 2024 May 29.

Abstract

Objectives: To calculate the shock index (SI) in dogs with myxomatous mitral valve disease (MMVD) and to evaluate its use to predict the presence of congestive heart failure (CHF).

Design: Retrospective study.

Setting: Small animal university veterinary teaching hospital.

Animals: Ninety-eight dogs with MMVD and 20 healthy dogs as part of a control group.

Interventions: Heart rate (HR) and systolic blood pressure (SBP) were recorded, and SI was calculated by dividing HR by SBP for each dog.

Measurements and main results: The mean (SD) HR, SBP, and SI were 123/min (32.6), 147 mm Hg (21.5), and 0.86 (0.3), respectively, for dogs with MMVD and 98/min (20.9), 145 mm Hg (18.7), and 0.68 (0.13), respectively, for control dogs. Dogs with MMVD had a significantly higher HR compared with control dogs (P < 0.01), and an elevation in HR was seen as the severity of MMVD increased. Dogs in stage B2 and C/D MMVD had a significantly higher SI value compared with control dogs (P = 0.04 and P < 0.01, respectively). SI was significantly higher in dogs in stage C/D MMVD compared with dogs in stage B2 MMVD (P < 0.01). Ten of 98 (10%) dogs had an arrhythmia. HR, SBP, and SI were not significantly different between dogs with and without arrhythmias (P = 0.13, P = 0.57, and P = 0.07, respectively), but significantly more dogs with CHF had an arrhythmia (P = 0.01). SI (area under the curve [AUC]: 0.98) and HR (AUC: 0.95) were excellent indicators for the presence of CHF. An optimal SI cutoff value ≥1.1 had 92% sensitivity and 95% specificity for predicting the presence of CHF, and an optimal HR cutoff value of ≥157/min had 92% sensitivity and 93% specificity for the prediction of CHF.

Conclusions: When there are compatible clinical signs, SI values ≥1.1 may suggest the presence of CHF in dogs with MMVD.

Keywords: canine; heart rate; pulmonary hypertension; shock; valve disease.

MeSH terms

  • Animals
  • Blood Pressure / physiology
  • Case-Control Studies
  • Dog Diseases* / diagnosis
  • Dogs
  • Female
  • Heart Failure* / veterinary
  • Heart Rate / physiology
  • Male
  • Mitral Valve Insufficiency / veterinary
  • Retrospective Studies