In recent years, exosomes had been recognized as a potential cell-free therapeutic tool in the field of regenerative medicine due to their easy accessibility, low immunogenicity, and good therapeutic effect. As paracrine products of cells, exosomes not only have the functions of their donor cells but also involve fewer ethical disputes. They are more stable than traditional stem cell therapy, and easy to store, transport and sterilize, which are gradually applied in the field of oral regenerative medicine. This article provides a review of the general properties of exosomes and their application in the field of oral regeneration, with a view to exploring new pathways for functional regeneration of the stomatognathic system.
近年来，外泌体因其易获取、低免疫原性和治疗效果佳等特性被认为是再生医学领域潜在的无细胞治疗工具。作为细胞的旁分泌产物，外泌体不仅具有其供体细胞的功能，且涉及的伦理学纠纷较少，外泌体用于治疗比传统干细胞治疗更加稳定，且其易于保存、运输、灭菌等，因此逐渐应用于口腔再生医学领域。本文就外泌体的一般特性及其在口腔再生领域的应用进行综述，以期探索口颌系统功能性再生的新路径。.