1 Keenan Research Centre for Biomedical Science and the Li Ka Shing Knowledge Institute, St. Michael's Hospital, Unity Health Toronto, Toronto, ON, Canada.
2 Department of Critical Care Medicine, Bhumibol Adulyadej Hospital, Bangkok, Thailand.
3 Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, ON, Canada.
4 Keenan Research Centre for Biomedical Science and the Li Ka Shing Knowledge Institute, St. Michael's Hospital, Unity Health Toronto, Toronto, ON, Canada. karen.burns@unityhealth.to.
5 Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, ON, Canada. karen.burns@unityhealth.to.
6 Keenan Research Centre for Biomedical Science and the Li Ka Shing Knowledge Institute, St. Michael's Hospital, Unity Health Toronto, Toronto, ON, Canada. haibo.zhang@unityhealth.to.
7 Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, ON, Canada. haibo.zhang@unityhealth.to.
8 Department of Physiology, University of Toronto, Toronto, ON, Canada. haibo.zhang@unityhealth.to.
9 Department of Anesthesiology and Pain Medicine, University of Toronto, Toronto, ON, Canada. haibo.zhang@unityhealth.to.